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5G；IMT-2020；关键技术；标准；现场试验 1

5G；交叉振子；双极化天线；终端天线；超宽带 1

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G-quadruplex formation of oligonucleotides containing ALS and FTD related GGGGCC repeat

Jasna Brčić,Janez Plavec

《化学科学与工程前沿（英文）》 2016年第10卷第2期页码 222-237 doi: 10.1007/s11705-016-1556-4

摘要： A largely increased number of GGGGCC repeats located in the non-coding region of gene have been identified as the leading cause of two related neurological disorders, familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). We examined G-quadruplex forming ability of GGGGCC-repeat containing oligonucleotides with four guanine tracts chosen as the smallest possible model to form a unimolecular G-quadruplex. These oligonucleotides are readily to folded into G-quadruplexes in the presence of K ions. However, the formation of multiple structures makes structural analysis challenging and time consuming. We observed that flanking sequences on 5'- and 3'-ends as well as mutations of loop residues have a profound effect on folding. Sequence d[(G C ) G ] was chosen for further scrutiny and optimization of nuclear magnetic resonance (NMR) spectroscopic properties with dG to 8Br-dG substitutions at specific positions in the sequence under different folding conditions. Expectedly, folding into desired predominant topology is facilitated when substituted residue adopted a conformation in the naturally-occurring structure. Single dG to 8Br-dG substitution at position 21 and fine tuning of folding conditions facilitate folding of d[(G C ) GG GG] into (mostly) a single G-quadruplex, and thus enable determination of its high-resolution structure by high-field NMR.

关键词： G-quadruplex GGGGCC NMR ALS/FTD polymorphism

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5′-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I

《医学前沿（英文）》 2023年第17卷第3期页码 476-492 doi: 10.1007/s11684-022-0966-6

摘要： tRNA-derived small RNAs (tsRNAs) are novel non-coding RNAs that are involved in the occurrence and progression of diverse diseases. However, their exact presence and function in hepatocellular carcinoma (HCC) remain unclear. Here, differentially expressed tsRNAs in HCC were profiled. A novel tsRNA, tRNA^Gln-TTG derived 5′-tiRNA-Gln, is significantly downregulated, and its expression level is correlated with progression in patients. In HCC cells, 5′-tiRNA-Gln overexpression impaired the proliferation, migration, and invasion in vitro and in vivo, while 5′-tiRNA-Gln knockdown yielded opposite results. 5′-tiRNA-Gln exerted its function by binding eukaryotic initiation factor 4A-I (EIF4A1), which unwinds complex RNA secondary structures during translation initiation, causing the partial inhibition of translation. The suppressed downregulated proteins include ARAF, MEK1/2 and STAT3, causing the impaired signaling pathway related to HCC progression. Furthermore, based on the construction of a mutant 5′-tiRNA-Gln, the sequence of forming intramolecular G-quadruplex structure is crucial for 5′-tiRNA-Gln to strongly bind EIF4A1 and repress translation. Clinically, 5′-tiRNA-Gln expression level is negatively correlated with ARAF, MEK1/2, and STAT3 in HCC tissues. Collectively, these findings reveal that 5′-tiRNA-Gln interacts with EIF4A1 to reduce related mRNA binding through the intramolecular G-quadruplex structure, and this process partially inhibits translation and HCC progression.

关键词： EIF4A1 G-quadruplex hepatocellular carcinoma tRNA-derived small RNA translation initiation

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2020普遍通信与5G技术国际会议(UC5G 2020)

会议日期： 2020年03月26日

会议地点：上海

主办单位： APISE

邹玉龙：5G/6G异构网络通信安全及电力物联网应用（2020年8月17日）

2022年10月17日

关键词：信息技术

CORRECTION to: A global carbon market?

Michael G. POLLITT

《工程管理前沿（英文）》页码 699-699 doi: 10.1007/s42524-019-0050-3

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2020年5G移动通信与信息科学国际学术会议（MCIS-5G2020）

会议日期： 2020年06月26日

会议地点：广东广州

一种用于用户端设备且工作在2G/3G/4G/IMT/5G频段的小型化超宽带交叉振子天线 Correspondences

郭景丽1,崔伦1,刘英1,孙保华1,李肖锋2

《信息与电子工程前沿（英文）》 2022年第23卷第2期页码 339-345 doi: 10.1631/FITEE.2000456

摘要：设计了一种用于用户端设备（CPE）且工作在2G/3G/4G/IMT/5G频段的小型化超宽带交叉振子天线。此外，通过在交叉振子下方增加开缝的寄生贴片，天线整体的带宽能够扩展到5G sub-6 GHz频段。此外，对天线结构进行了加工和测试。

关键词： 5G；交叉振子；双极化天线；终端天线；超宽带

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Special issue on 5G wireless communication systems and technologies Editorial

Ping ZHANG

《信息与电子工程前沿（英文）》 2017年第18卷第6期页码 751-752 doi: 10.1631/FITEE.1720000

摘要： None

关键词： None

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Microwave assisted synthesis of poly(2-hydroxyethylmethacrylate) grafted agar (Ag-g-P(HEMA)) and its

Gautam SEN, G. Usha RANI, Sumit MISHRA

《化学科学与工程前沿（英文）》 2013年第7卷第3期页码 312-321 doi: 10.1007/s11705-013-1344-3

摘要： Poly(2-hydroxyethylmethacrylate) chains were grafted onto the backbone of agar using a microwave assisted method involving a combination of microwave irradiation and ceric ammonium nitrate to initiate the grafting reaction. The synthesized graft copolymers were characterized by intrinsic viscosity measurements, Fourier transform infrared spectroscopy, elemental analysis (C, H, N, O and S) and scanning electron microscopy. Ag-g-P(HEMA)-2 showed a much higher flocculation efficacy than agar. The optimized dosage of flocculation for Ag-g-P(HEMA)-2 in the wastewater was found to be 0.75 ppm. Compared to agar, Ag-g-P(HEMA)-2 was found to considerably reduce the pollutant load in the wastewater.

关键词： agar flocculant microwave assisted synthesis jar test protocol poly(HEMA) grafted agar wastewater treatment

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reduces IgE binding ability of allergenic egg white proteins

Sen LI, Marina OFFENGENDEN, Michael G. GÄNZLE, Jianping WU

《农业科学与工程前沿（英文）》 2018年第5卷第3期页码 373-381 doi: 10.15302/J-FASE-2018210

摘要：

Egg white proteins are one of the major allergens. The objective of this study was to investigate the effect of Aspergillus oryzae cultivation on IgE binding ability of egg white proteins. Effect of A. oryzae on egg white proteins was determined using ninhydrin method, SDS-PAGE, ELISA, fluorescence FITC labeling, MALDI-TOF-MS and LC-MS/MS analysis. Adding mycelium of A. oryzae ATCC 1011 and 16868 substantially reduced the IgE binding ability of acidified egg white after 24 h incubation. The binding capacity of egg white proteins to IgE in plasma from four egg allergy patients was almost completely lost after incubation with mycelium of ATCC 16868. Results from SDS-PAGE, free amino acid analysis, MALDI-TOF-MS and LC-MS/MS indicated that there was no substantial protein degradation during incubation. Therefore, the reduction of IgE binding ability of egg white proteins during A. oryzae treatment was probably due to a loss of ~1700 Da mass including a fragment of the ovomucoid N terminus.

关键词： Aspergillus oryzae egg allergy egg white proteins IgE-binding ability ovomucoid

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5G将带来哪些改变？

Erika K. Carlson

《工程（英文）》 2020年第6卷第7期页码 725-727 doi: 10.1016/j.eng.2020.05.012

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5G综述及中国的进展 None

Shan-zhi CHEN, Shao-li KANG

《信息与电子工程前沿（英文）》 2018年第19卷第3期页码 309-321 doi: 10.1631/FITEE.1800070

摘要： 5G技术、标准和产业化从20012年开始高速发展，是全球经济新的驱动力。本文全面介绍了5G，包括愿景、要求、演进、关键技术、标准化、频谱分配、技术试验、产业化进展和5G主要贡献者。同时指出，中国企业作为5G主要技术和标准的贡献者，正处于“5G引领”过程中。最后介绍了5G最新进展和作者关于5G的再思考。

关键词： 5G；IMT-2020；关键技术；标准；现场试验

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5G最小代价多播网络中的次优编码子图算法 None

Feng WEI, Wei-xia ZOU

《信息与电子工程前沿（英文）》 2018年第19卷第5期页码 662-673 doi: 10.1631/FITEE.1700020

摘要：为降低具有控制—数据分离架构的5G网络中多播的传输代价，本文关注无线网络中两多播共存时的功率代价最小网络编码子图形成问题。

关键词：网络编码子图；最小功率代价；5G；分离架构

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Biogas and its opportunities—A review

Panagiotis G. Kougias, Irini Angelidaki

《环境科学与工程前沿（英文）》 2018年第12卷第3期 doi: 10.1007/s11783-018-1037-8

摘要： Biogas production is a well-established technology primarily for the generation of renewable energy and also for the valorization of organic residues. Biogas is the end product of a biological mediated process, the so called anaerobic digestion, in which different microorganisms, follow diverse metabolic pathways to decompose the organic matter. The process has been known since ancient times and was widely applied at domestic households providing heat and power for hundreds of years. Nowadays, the biogas sector is rapidly growing and novel achievements create the foundation for constituting biogas plants as advanced bioenergy factories. In this context, the biogas plants are the basis of a circular economy concept targeting nutrients recycling, reduction of greenhouse gas emissions and biorefinery purposes. This review summarizes the current state-of-the-art and presents future perspectives related to the anaerobic digestion process for biogas production. Moreover, a historical retrospective of biogas sector from the early years of its development till its recent advancements gives an outlook of the opportunities that are opening up for process optimisation.

关键词： Anaerobic digestion Biogas Biowastes Solid waste Manure Industrial waste